Myeloperoxidase

Understanding Myeloperoxidase (MPO) in Your Lab Results

Myeloperoxidase (MPO) is an enzyme found in white blood cells that plays a crucial role in the body's immune response. Elevated levels of MPO in the blood can be an indicator of inflammation and have been linked to an increased risk of cardiovascular diseases. Understanding your MPO levels can provide valuable insights into your heart health and help guide lifestyle and medical decisions.

What is Myeloperoxidase?

MPO is an enzyme produced by certain types of white blood cells, primarily neutrophils. It helps the body fight off infections by producing substances that kill bacteria and other pathogens. However, when MPO levels are too high, it can lead to excessive inflammation, which is a risk factor for atherosclerosis—a condition where arteries become clogged with fatty deposits, potentially leading to heart attacks or strokes.

Factors Influencing MPO Levels

Several lifestyle and nutritional factors can influence MPO levels. Diets high in saturated fats and trans fats can increase inflammation and, consequently, MPO levels. Conversely, consuming a diet rich in fruits, vegetables, whole grains, and omega-3 fatty acids can help reduce inflammation. Regular physical activity, maintaining a healthy weight, and avoiding smoking are also important in managing MPO levels. Stress management techniques, such as meditation and yoga, may further help in keeping inflammation at bay.

Medical Conditions Associated with Abnormal MPO Levels

Abnormal MPO levels can be associated with various medical conditions. Elevated MPO levels are often found in individuals with cardiovascular diseases, such as coronary artery disease and heart failure. They may also be seen in inflammatory conditions like rheumatoid arthritis and inflammatory bowel disease. Monitoring MPO levels can be an important part of managing these conditions and assessing the risk of developing heart disease.

Normal Ranges for Myeloperoxidase

The normal range for MPO levels can vary depending on the laboratory and the specific testing methods used. However, generally, MPO levels are considered normal when they are below 500 picograms per milliliter (pg/mL). Levels above this threshold may indicate increased inflammation and a higher risk of cardiovascular issues. It is important to discuss your specific results with your healthcare provider to understand what they mean for your health.

Understanding your MPO levels can be a key component in assessing your risk for heart disease and other inflammatory conditions. By making informed lifestyle choices and working with your healthcare provider, you can take proactive steps to manage your health effectively.